Dolittle is a 2020 American fantasy adventure film directed by Stephen Gaghan from a screenplay by Gaghan, Dan Gregor, and Doug Mand, based on a story by Thomas Shepherd. Dolittle is based on the title character created by Hugh Lofting and is primarily inspired by the author's second Doctor Dolittle book, The Voyages of Doctor Dolittle (1922). Robert Downey Jr. stars as the title character, alongside Antonio Banderas and Michael Sheen in live-action roles, with Emma Thompson, Rami Malek, John Cena, Kumail Nanjiani, Octavia Spencer, Tom Holland, Craig Robinson, Ralph Fiennes, Selena Gomez, and Marion Cotillard voicing an array of creatures.